The U.S.-Israel-Iran War is well underway, and the risks of spillover and enlargement is becoming more of a reality as the war goes on. As the conflict continues to expand, several actors are seeking out opportunities to challenge the existing balance of power in the region and aim to exploit the war to expand their influence. In the past decade, Russia has been working to court the United States’ MENA allies into its sphere of influence through the concept of regime stability, while China is taking on a soft power approach through economic and diplomatic cooperation. A prolonged war between the U.S.-Israel and Iran can result in global powers such as Russia and China getting more involved in the region to diminish American influence globally, which can result in a great power competition. The potential of Iran serving as an arena for great power competition will be explored through the American strategic overstretch and the economic shock caused by energy crisis.