The United States entered the second week of its joint military campaign against Iran on March 7, 2026, having launched Operation Epic Fury alongside Israel on February 28. Within days, the conflict had killed Supreme Leader Ali Khamenei, triggered Iranian retaliatory strikes across the Gulf, and drawn in regional powers from Bahrain to Lebanon. For the Republican Party, the war arrived at what was already an exceptionally precarious moment — one in which the historical forces of midterm politics, falling presidential approval, and a restless voter coalition had already conspired against them. The onset of a major, unpopular war has only deepened those vulnerabilities, and the question facing the GOP heading into November is no longer simply whether they will lose seats, but how many.